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Mechanism 1: Mitochondrial Oxidative Stress EGCG at high concentrations generates reactive oxygen species (ROS) inside hepatocytes, a mechanism documented in multiple cell-culture and rodent studies [7]

Serious or Rare Side Effects to Watch For While rare, some side effects require immediate attention

In our study in rheumatoid arthritis, we saw that nearly one-third of patients actually discontinued therapy within a year, and most commonly that was due to gastrointestinal or GI symptoms

He was not part of the study but also reviewed the findings

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Compared to placebo, tirzepatide showed the greatest reduction in HbA1-c (MD: -2.3%) and FPG (MD: -3.1mmol/L)